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Institute for Regenerative Medicine • IREM

Clinical translation stem cell gene therapy

Research Focus

We have developed a novel lentiviral self-inactivated (SIN) vector for treatment of hematopoietic stem cells to treat patients with an inborn immunodeficiency of phagocytes, chronic granulomatous disease (CGD). Our team is preparing an international first-in-man clinical trial to treat patients with autosomal-recessive CGD. The gene therapy medicinal product will be produced by our translational team under GMP (good manufacturing practice), at the Wyss Zurich Translational centre.

Group Members

Research Associates
Oleksandr Pastukhov
Federica Raimondi
Panagiotis Tsapogas
Dominik Wrona

Davidané Kress
Stacy da Silva Duarte