Laboratory for Aging Neuroscience and Neuroimaging

Laboratory for Aging Neuroscience and Neuroimaging

The main research interest of our group is the characterisation of early clinical phenotypes associated with increased risk for development of dementia and Alzheimer Disease (AD) in particular.

Our group investigates elderly clinical populations with and without cognitive impairment. In this context our group has implemented state of the art neuroimaging technologies, including MRI-contrasts at 3 and 7 Tesla, as well as PET. Moreover, we have been using genetic and metabolic information for characterisation of subgroups with increased risk for AD.

While our group currently consists of three PhD students and two MDs, we have been closely collaborating with basic science groups at Department of Nuclear Medicine, USZ (Prof. A. Buck), Institute for Biomedical Engineering (IBT) (Prof. Klaas Pruessmann) and École polytechnique fédérale de Lausanne (Prof. D. Van de Ville), as well as F.M. Kirby Center for Functional Brain imaging at KKI, Johns Hopkins University (Prof. Peter Van Zijl), Stanley Center for Psychiatric Research at Broad Institute, MIT/HMS (Stephan Ripke, MD) and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia (Prof. Adam Brickman).

PD Dr. med. Paul G. Unschuld

7T MRI Metabolomics