Old News (Archive)

Generali M. et al.: "Heterogeneous Expression of ACE2 and TMPRRS2 in Mesenchymal Stromal Cells" in Journal of Cellular and Molecular Medicine

Sun, 28 Nov 2021 23:00:00 GMT

IREM at Science Agora

Mon, 18 Oct 2021 22:00:00 GMT

From Earth to Space to Earth: From Regenerative Medicine to Biodiversity – Science from Switzerland

iPSC Core Facility at IREM

Melanie Generali — Mon, 13 Sep 2021 22:00:00 GMT

The Institute for Regenerative Medicine, which has the mission to advance molecular life sciences into next generation therapies, established recently the iPSC Core Facility to promote this powerful technology at the UZH and other institutions.

New publication by Melanie Generali in Journal Genes

Melanie Generali — Mon, 13 Sep 2021 22:00:00 GMT

New insights into the biology of an aggressive pediatric cancer, which will help focus future research goals.

IREM to participate at Scientifica

Tue, 03 Aug 2021 22:00:00 GMT

Prof Martin Schwab will give this year's "Wings For Life" Lecture

Wed, 14 Jul 2021 22:00:00 GMT

"From the bench to clinical trials for a regeneration enhancing anti-Nogo-A antibody therapy for spinal cord injury"

FDA approval of Aducanumab for the treatment of Alzheimer’s disease

Sun, 06 Jun 2021 22:00:00 GMT

The Institute for Regenerative Medicine (IREM) is pleased to share the news that the U.S. Food and Drug Administration (FDA) has approved aducanumab for the treatment of Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia and accounts for 50-75% of all cases worldwide.

Ruslan Rust receives 3RCC Grant for "Experimental toolkit to evaluate cell-based therapies in the mouse brain"

Mon, 31 May 2021 22:00:00 GMT

New Minor in BioMedEntrepreneurship

Tue, 13 Apr 2021 13:02:48 GMT

Dr. Ramona Weber receives a HFSP postdoctoral long-term fellowship

Fri, 09 Apr 2021 13:52:01 GMT

URPP Kick-off Event 23 March 2021

Mon, 22 Feb 2021 16:08:36 GMT

New IREM seminar series Innovations in Regenerative Medicine

Tue, 16 Feb 2021 15:58:53 GMT

New Publication by Ruslan Rust in Journal of Cerebral Blood Flow and Metabolism

Mon, 08 Feb 2021 23:00:00 GMT

Harnessing cell therapies to fight COVID-19: Basic research, clinical evidence and patient access

Thu, 11 Feb 2021 13:33:49 GMT

https://www.restore-horizon.eu/covid-19-and-atmps-webinar/

BrainFair 15. - 19.März 2021

Fri, 29 Jan 2021 12:54:18 GMT

2nd IREM Scientific Art Photo Competition 2021

Thu, 07 Jan 2021 07:32:14 GMT

Ruslan Rust receives SNF Spark Grant to develop a brain-shuttle for cell therapies

Wed, 09 Dec 2020 23:00:00 GMT

Nature - Scientific Reports publication by M. Y. Emmert/ S. Motta and E. Fioretta (first authors)

Sun, 15 Nov 2020 23:00:00 GMT

"Geometry influences inflammatory host cell response and remodeling in tissue-engineered heart valves in-vivo”

Spark grant 2020-2021 awarded to Sarah Motta

Tue, 10 Nov 2020 23:00:00 GMT

“Rethinking multi-organ tissue-engineering: an in-vitro model to design regenerative native-like tissue-engineered heart valves”

New Publication by Rebecca Weber and Ruslan Rust in Frontiers in Physiology

Thu, 12 Nov 2020 23:00:00 GMT

"Characterization of the Blood Brain Barrier Disruption in the Photothrombotic Stroke Model"

Visiting Professor Sandra Loerakker

Wed, 30 Sep 2020 22:00:00 GMT

We welcome Professor Sandra Loerakker as a Visiting Professor at our institute.

New publication in Nature Reviews Cardiology by M.Y. Emmert and colleagues

Tue, 08 Sep 2020 22:00:00 GMT

Distinct changes in all major components of the neurovascular unit across different neuropathological stages of Alzheimer's disease

Thu, 03 Sep 2020 22:00:00 GMT

New University Research Priority Programs (URPP) ITINERARE

Thu, 27 Aug 2020 22:00:00 GMT

In order to underpin its position among the world’s leading research institutions, the University of Zurich has established its University Research Priority Programs (URPP). The URPP create and promote academic networks in selected areas of research and contribute to the advancement of knowledge in areas of research that benefit society.

Kyoto University and the University of Zurich have officially established a strategic partnership

Cornelia Schauz — Mon, 17 Aug 2020 22:00:00 GMT

Human Cardiac Organoids for Modeling Genetic Cardiomyopathy

Sun, 19 Jul 2020 22:00:00 GMT

New paper by Michele Filippo Buono, Lisa von Boehmer, Jaan Strang, Simon P. Hoerstrup, Maximilian Y. Emmert and Bramasta Nugraha, published on 20 July

New Minor in BioMed Entrepreneurship at IREM

Thu, 16 Jul 2020 11:18:54 GMT

Therapeutic antibodies targeting CNS : Comparative Study by Correa et al. of intrathecal, intravenous, and subcutaneous anti-Nogo A antibody treatment after stroke in rats

Cornelia Schauz — Wed, 13 May 2020 22:00:00 GMT

Anna S Wahl, Daphne Correa et.al. on ‘Targeting Therapeutic Antibodies to the CNS: A Comparative Study of Intrathecal, Intravenous, and Subcutaneous Anti-Nogo A Antibody Treatment after Stroke in Rats’, published in Neurotherapeutics

Wrona et al.: CRISPR-Directed Therapeutic Correction at the NCF1 Locus Is Challenged by Frequent Incidence of Chromosomal Deletions

Cornelia Schauz — Wed, 13 May 2020 22:00:00 GMT

Two of our IREM scientists – Debora Kehl and Ruslan Rust – have been selected to participate on the 70th Nobel Laureate Meeting

Cornelia Schauz — Mon, 06 Apr 2020 22:00:00 GMT

Once every year, around 30-40 Nobel Laureates and 600 excellent, young scientists from all around the world convene in Lindau, to foster the exchange among scientists of different generations, cultures and disciplines. This year’s 70th Nobel Laureate Meeting is an interdisciplinary meeting, where scientists from all three natural sciences – chemistry, physic and medicine – are united.

Ruslan Rust et al. in Frontiers in Neuroscience: A Practical Guide to the Automated Analysis of Vascular Growth, Maturation and Injury in the Brain

Tue, 31 Mar 2020 22:00:00 GMT

IREM Organization Update

Cornelia Schauz — Tue, 10 Mar 2020 23:00:00 GMT

Ruslan Rust et al. in JCBFM: "Insights Into the Dual Role of Angiogenesis Following Stroke"

Wed, 04 Mar 2020 23:00:00 GMT

Stroke remains a major cause of serious disability due to the brain’s limited capacity to regenerate.

New publication of Fioretta et al. in JACC: Basic to Translational Science.

Mon, 02 Mar 2020 23:00:00 GMT

Prof. Dr. Janine Reichenbach new associate professor for Somatic Gene Therapy

Fri, 31 Jan 2020 23:00:00 GMT

Prof. Dr. Janine Reichenbach has started as associate professor for Somatic Gene Therapy at the Institute for Regenerative Medicine (IREM), chairing this new division of the institute.

IREM Professor Janine Reichenbach is member of the new HMZ flagship project Immuno-TargET.

Thu, 09 Jan 2020 23:00:00 GMT

Autoimmune diseases and cancer have highly interesting parallels that can be used for novel therapeutic approaches. Tumours that originate from endocrine (hormone-producing) organs such as the thyroid gland, the parathyroid gland, the pituitary gland or the gastrointestinal tract are often characterised by excessive hormone production and frequently retain the functional and molecular properties of their originating organ.

IREM Professor Max Emmert receives Techno-College Innovation Award

Thu, 09 Jan 2020 23:00:00 GMT

IREM Professor Max Emmert received the Techno-College Innovation Award for the LifeMatrix, a human cell derived acellular engineered tissue platform.

Fixing Hearts, Saving Lives

Wed, 08 Jan 2020 23:00:00 GMT

Rust et al: Anti-Nogo-A antibodies prevent vascular leakage and act as pro-angiogenic factors following stroke.

Thu, 09 Jan 2020 23:00:00 GMT

In this study, we demonstrate that antibody-mediated Nogo-A neutralization following stroke has strong pro-angiogenic effects but does not increase vascular permeability as opposed to the Vascular Endothelial Growth Factor (VEGF). Moreover, VEGF-induced vascular permeability was partially prevented when VEGF was co-administered with anti-Nogo-A antibodies. This study may provide a novel therapeutic strategy for vascular repair and maturation in the ischemic brain.

Unconventional research and novel scientific approaches: Two Spark grants awarded to IREM researchers

Thu, 05 Dec 2019 23:00:00 GMT

In July 2019, the SNSF launched the funding scheme Spark as a pilot project to support unconventional research and novel scientific approaches. Each application was evaluated in a double-blind procedure by two members of an international pool of experts. It was the idea that counted most of all. Other important criteria were the quality of the submitted project proposal and the potential impact of the results.

First iPSC lecture will take place at the University of Zurich

Sun, 10 Nov 2019 23:00:00 GMT

We are delighted to announce that the first iPSC lecture will take place at the University of Zurich. This lecture series will provide a forum to disseminate state-of-the-art iPSC research, build relationships with one-another, renew and establish collaborations and strategies. Experts in the field of iPSC technology will share their knowledge.

New analysis of study results showed clinical benefit of Aducanumab

Tue, 22 Oct 2019 22:00:00 GMT

October 23, 2019 -- IREM is pleased to learn that Biogen plans regulatory filing for aducanumab in Alzheimer's disease based on a new analysis of a larger data set from Phase 3 studies. Neurimmune, a spin-out company of the University of Zurich, discovered aducanumab together with a research group at the University of Zurich that went on to co-found IREM. In 2007 Neurimmune and Biogen entered into a collaborative development and license agreement for aducanumab's development and commercialization.

UZH IncubatorLab: Mit Era-107 den Appetit sanft bändigen

Mon, 09 Sep 2019 22:00:00 GMT

Viele Schlankheitsmittel sind gesundheitsschädlich oder zu wenig wirksam. Nun entwickelt ein Startup der UZH einen Appetithemmer, der keine unerwünschten Nebenwirkungen hervorruft und das Gewicht im Vergleich zu zugelassenen Standardmedikamenten im Tiermodell doppelt so stark reduziert.

ISACB+ISVTE conference abstracts published

Wed, 04 Sep 2019 22:00:00 GMT

The International Symposium for Applied Cardiovascular Biology and Vascular Tissue Engineering (ISACB+ISVTE) has successfully come to an end.

ERC Starting Grant awarded to Prof. Maximilian Emmert

Mon, 02 Sep 2019 22:00:00 GMT

S. Motta et al.: Human cell-derived tissue-engineered heart valve with integrated Valsalva sinuses: towards native-like transcatheter pulmonary valve replacements; new publication in npj Regenerative Medicine - Nature.

Sun, 01 Sep 2019 22:00:00 GMT

Autologous endothelialized small-caliber vascular grafts engineered from blood-derived induced pluripotent stem cells

Mon, 29 Jul 2019 22:00:00 GMT

Rust et al: Review on Therapeutic Angiogenesis in «Trends in Neurosciences»

Sun, 07 Jul 2019 22:00:00 GMT

Sherida de Leeuw and Christian Tackenberg, “Alzheimer’s in a dish – Induced pluripotent stem cell-based disease modeling”, published in Translational Neurodegeneration

Thu, 11 Jul 2019 22:00:00 GMT

Frank Baaijens, Rektor TU Eindhoven and Visiting Professor IREM: Die TU Eindhoven stellt nur noch Frauen ein.

Wed, 03 Jul 2019 22:00:00 GMT