CNS angiogenesis and Neurovascular link

Research Focus:

We aim to understand the cellular and molecular mechanisms that govern angiogenesis and the neurovascular unit/perivascular niche in the central nervous system (CNS), during development as well as in CNS pathologies such as brain tumors and vascular malformations. 
Current projects focus on the mechanisms that regulate angiogenesis, endothelial tip cells and the neurovascular unit/perivascular niche during brain development and in the above-mentioned CNS pathologies. To that regard, we are also investigating the differences between developmental and pathological blood vessel formation. 

We use interdisciplinary approaches combining in vivo and in vitro techniques as well as mouse and human tissues in order to translate the laboratory findings into clinically relevant settings such as brain tumors, vascular malformations, and stroke.