Publications since 2008

2018

Rust R, Gantner C, Schwab ME (2018). Pro- and antiangiogenic therapies: current status and clinical implications. FASEB J. 2018 Aug 7:fj201800640RR

Fregosi M, Contestabile A, Badoud S, Borgognon S, Cottet J, Brunet JF, Bloch J, Schwab ME, Rouiller EM (2018). Changes of motor corticobulbar projections following different lesion types affecting the central nervous system in adult macaque monkeys. Eur J Neurosci. 2018 Aug;48(4):2050-2070.

Rust R, Hofer AS, Schwab ME (2018). Stroke Promotes Systemic Endothelial Inflammation and Atherosclerosis. Trends Mol Med. 2018 Jul;24(7):593-595.

Berry S, Weinmann O, Fritz AK, Rust R, Wolfer D, Schwab ME, Gerber U, Ster J (2018). Loss of Nogo-A, encoded by the schizophrenia risk gene Rtn4, reduces mGlu3 expression and causes hyperexcitability in hippocampal CA3 circuits. PLoS One. 2018 Jul 24;13(7):e0200896.

Holm MM, Kaiser J, Schwab ME (2018). Extracellular Vesicles: Multimodal Envoys in Neural Maintenance and Repair. Trends Neurosci. 2018 Jun;41(6):360-372.

Zemmar A, Chen CC, Weinmann O, Kast B, Vajda F, Bozeman J, Isaad N, Zuo Y, Schwab ME (2018). Oligodendrocyte- and Neuron-Specific Nogo-A Restrict Dendritic Branching and Spine Density in the Adult Mouse Motor Cortex. Cereb Cortex. 2018 Jun 1;28(6):2109-2117.

Kucher K, Johns D, Maier D, Abel R, Badke A, Baron H, Thietje R, Casha S, Meindl R, Gomez-Mancilla B, Pfister C, Rupp R, Weidner N, Mir A, Schwab ME, Curt A (2018). First-in-Man Intrathecal Application of Neurite Growth-Promoting Anti-Nogo-A Antibodies in Acute Spinal Cord Injury. Neurorehabil Neural Repair. 2018 Jun;32(6-7):578-589.

Wahl AS, Erlebach E, Brattoli B, Büchler U, Kaiser J, Ineichen BV, Mosberger AC, Schneeberger S, Imobersteg S, Wieckhorst M, Stirn M, Schroeter A, Ommer B, Schwab ME (2018). Early reduced behavioral activity induced by large strokes affects the efficiency of enriched environment in rats. J Cereb Blood Flow Metab. 2018 May 17:271678X18777661

Schneider MP, Sartori AM, Tampé J, Moors S, Engmann AK, Ineichen BV, Hofer AS, Schwab ME, Kessler TM (2018). Urodynamic measurements reflect physiological bladder function in rats. Neurourol Urodyn. 2018 Apr;37(4):1266-1271.

Mosberger AC, Miehlbradt JC, Bjelopoljak N, Schneider MP, Wahl AS, Ineichen BV, Gullo M, Schwab ME (2018). Axotomized Corticospinal Neurons Increase Supra-Lesional Innervation and Remain Crucial for Skilled Reaching after Bilateral Pyramidotomy. Cereb Cortex. 2018 Feb 1;28(2):625-643.

2017

Zemmar A, Chen CC, Weinmann O, Kast B, Vajda F, Bozeman J, Isaad N, Zuo Y, Schwab ME (2017).Oligodendrocyte- and Neuron-Specific Nogo-A Restrict Dendritic Branching and Spine Density in the Adult Mouse Motor Cortex. Cereb Cortex. 2017 May 15:1-9.

Ineichen BV, Kapitza S, Bleul C, Good N, Plattner PS, Seyedsadr MS, Kaiser J, Schneider MP, Zörner B, Martin R, Linnebank M, Schwab ME (2017).Nogo-A antibodies enhance axonal repair and remyelination in neuro-inflammatory and demyelinating pathology. Acta Neuropathol. 2017 Jun 23.

Corbett D, Carmichael ST, Murphy TH, Jones TA, Schwab ME, Jolkkonen J, Clarkson AN, Dancause N, Weiloch T, Johansen-Berg H, Nilsson M, McCullough LD, Joy MT (2017).Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable translational working group. Int J Stroke. 2017 Jul;12(5):462-471.

Kempf A, Boda E, Kwok JCF, Fritz R, Grande V, Kaelin AM, Ristic Z, Schmandke A, Schmandke A, Tews B, Fawcett JW, Pertz O, Buffo A, Schwab ME (2017).Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction. Dev Cell. 2017 Oct 9;43(1):24-34.e5.

Wahl AS, Büchler U, Brändli A, Brattoli B, Musall S, Kasper H, Ineichen BV, Helmchen F, Ommer B, Schwab ME (2017).Optogenetically stimulating intact rat corticospinal tract post-stroke restores motor control through regionalized functional circuit formation. Nat Commun. 2017 Oct 30;8(1):1187.

Schneider MP, Sartori AM, Tampé J, Moors S, Engmann AK, Ineichen BV, Hofer AS, Schwab ME, Kessler TM (2017).Urodynamic measurements reflect physiological bladder function in rats. Neurourol Urodyn. 2017 Nov 15.

Wälchli T, Ulmann-Schuler A, Hintermüller C, Meyer E, Stampanoni M, Carmeliet P, Emmert MY, Bozinov O, Regli L, Schwab ME, Vogel J, Hoerstrup SP.Nogo-A regulates vascular network architecture in the postnatal brain. J Cereb Blood Flow Metab. 2017 Feb;37(2):614-631. doi: 10.1177/0271678X16675182. Epub 2016 Nov 13.

Ineichen BV, Schnell L, Gullo M, Kaiser J, Schneider MP, Mosberger AC, Good N, Linnebank M, Schwab ME.Direct, long-term intrathecal application of therapeutics to the rodent CNS. Nat Protoc. 2017 Jan;12(1):104-131. doi: 10.1038/nprot.2016.151. Epub 2016 Dec 15.

Ineichen BV, Weinmann O, Good N, Plattner PS, Wicki C, Rushing EJ, Linnebank M, Schwab ME.Sudan black: a fast, easy and non-toxic method to assess myelin repair in demyelinating diseases. Neuropathol Appl Neurobiol. 2017 Apr;43(3):242-251. doi: 10.1111/nan.12373. Epub 2017 Mar 10.

Mosberger AC, Miehlbradt JC, Bjelopoljak N, Schneider MP, Wahl AS, Ineichen BV, Gullo M, Schwab ME.Axotomized Corticospinal Neurons Increase Supra-Lesional Innervation and Remain Crucial for Skilled Reaching after Bilateral Pyramidotomy. Cereb Cortex. 2017 Jan 8. doi: 10.1093/cercor/bhw405.

Ineichen BV, Plattner PS, Good N, Martin R, Linnebank M, Schwab ME.Nogo-A Antibodies for Progressive Multiple Sclerosis. CNS Drugs. 2017 Mar;31(3):187-198. doi: 10.1007/s40263-017-0407-2.

Chen K, Marsh BC, Cowan M, Al'Joboori YD, Gigout S, Smith CC, Messenger N, Gamper N, Schwab ME, Ichiyama RM.Sequential therapy of anti-Nogo-A antibody treatment and treadmill training leads to cumulative improvements after spinal cord injury in rats. Exp Neurol. 2017 Jun;292:135-144. doi: 10.1016/j.expneurol.2017.03.012. Epub 2017 Mar 21.

Hlavica M, Delparente A, Good A, Good N, Plattner PS, Seyedsadr MS, Schwab ME, Figlewicz DP, Ineichen BV.Intrathecal insulin-like growth factor 1 but not insulin enhances myelin repair in young and aged rats. Neurosci Lett. 2017 May 1;648:41-46. doi: 10.1016/j.neulet.2017.03.047. Epub 2017 Mar 29.

2016

Zelenay V, Arzt ME, Bibow S, Schwab ME, Riek R.The Neurite Outgrowth Inhibitory Nogo-A-Δ20 Region Is an Intrinsically Disordered Segment Harbouring Three Stretches with Helical Propensity. PLoS One. 2016 Sep 9;11(9):e0161813. doi: 10.1371/journal.pone.0161813. eCollection 2016.

Kellner Y, Fricke S, Kramer S, Iobbi C, Wierenga CJ, Schwab ME, Korte M, Zagrebelsky M (2016).Nogo-A controls structural plasticity at dendritic spines by rapidly modulating actin dynamics. Hippocampus. 2016 Jan 7. doi: 10.1002/hipo.22565.

Freund P, Friston K, Thompson AJ, Stephan KE, Ashburner J, Bach DR, Nagy Z, Helms G, Draganski B, Mohammadi S, Schwab ME, Curt A, Weiskopf N (2016).Embodied neurology: an integrative framework for neurological disorders. Brain. 2016 Jun;139(Pt 6):1855-61.

Mosberger AC, de Clauser L, Kasper H, Schwab ME (2016).Motivational state, reward value, and Pavlovian cues differentially affect skilled forelimb grasping in rats. Learn Mem. 2016 May 18;23(6):289-302.

Dietz V, Schwab ME (2016).From the rodent spinal cord injury model to human application: Promises and challenges. J Neurotrauma. 2016 Jun 10.

2015

Filli L, Engmann AK, Zörner B, Weinmann O, Moraitis T, Gullo M, Kasper H, Schneider R, Schwab ME (2015).Bridging the gap: a reticulo-propriospinal detour bypassing an incomplete spinal cord injury. J Neurosci. 34(40):13399-410.

Guzik-Kornacka A, van der Bourg A, Vajda F, Joly S, Christ F, Schwab ME, Pernet V (2014).Nogo-A deletion increases the plasticity of the optokinetic response and changes retinal projection organization in the adult mouse visual system. Brain Struct Funct. [Epub ahead of print].

Zemmar A, Kast B, Lussi K, Luft AR, Schwab ME (2015).Acquisition of a high-precision skilled forelimb reaching task in rats. J Vis Exp. (100).

Thiede-Stan NK, Tews B, Albrecht D, Ristic Z, Ewers H, Schwab ME. (2015).Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex. J Cell Sci. 128(19):3583-96.

Thiede-Stan NK, Schwab ME (2015). Attractive and repulsive factors act through multi-subunit receptor complexes to regulate nerve fiber growth. J Cell Sci. 128(14):2403-14.

Filli L, Schwab ME (2015).Structural and functional reorganization of propriospinal connections promotes functional recovery after spinal cord injury. Neural Regen Res. 10(4):509-13.

Wälchli T, Wacker A, Frei K, Regli L, Schwab ME, Hoerstrup SP, Gerhardt H, Engelhardt B (2015).Wiring the vascular network with neural cues: a CNS perspective. Neuron. 87(2):271-96.

Silver J, Schwab ME, Popovich PG (2015). Central nervous system regenerative failure: role of oligodendrocytes, astrocytes, and microglia. In: Cold spring harbor perspectives in biology (Barres BA et al., eds), pp 425-443. Cold spring harbor, New York.

Schneider MP, Hughes FM Jr, Engmann AK, Purves JT, Kasper H, Tedaldi M, Spruill LS, Gullo M, Schwab ME, Kessler TM (2015). A novel urodynamic model for lower urinary tract assessment in awake rats. Br.J.Urol. .115 Suppl 6:8-15

Wälchli T, Mateos JM, Weinman O, Babic D, Regli L, Hoerstrup SP, Gerhardt H, Schwab ME, Vogel J (2015). Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain.Nature Protoc; 20:53-74

Schneider MP, Schwab ME, Kessler TM (2015). Anti-Nogo-A antibody: a treatment option for neurogenic lower urinary tract dysfunction? Br.J.Urol.; 115 Suppl 6:16-7

Vajda F, Jordi N, Dalkara D, Joly S, Christ F, Tews B, Schwab ME, Pernet V (2015). Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve.Cell Death Differ; 22:323-35

2014

Zemmar A., Weinmann O, Kellner Y, Yu X, Vincente R, Gullo M, Kasper HJ, Lussi K, Ristic Z, Luft AR, Rioult-Pedotti M, Zuo Y, Zagrebelsky M, Schwab ME (2014). Neutralization of Nogo-A Enhances Synaptic Plasticity in the Rodent Motor Cortex and Improves Motor Learning in Vivo. The Journal of Neuroscience 34(26): 8685- 8698.

Wahl AS, Omlor W, Rubio JC, Chen JL, Zheng H, Schröter A, Gullo M, Weinmann O, Kobayashi K, Helmchen F, Ommer B, Schwab ME (2014). Neuronal repair. Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke. Science 13;344(6189):1250-5.

Schwab ME, Strittmatter SM (2014). Nogo limits neural plasticity and recovery from injury. Neurobiology 27:53-60

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Petrasek T, Prokopova I, Sladek M, Weissova K, Vojtechova I, Bahnik S, Zemanova A, Schönig K, Berger S, Tews B, Bartsch D, Schwab ME, Sumova A, Stuchlik A (2014). Nogo A deficient transgenic rats show deficits in higher cognitive functions, decreased anxiety, and altered circadian activity patterns. Frontiers 8: 1-15

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Schmandke A, Schmandke A, Schwab ME (2014). Nogo-A Multiple: Roles in CNS Development, Maintenance, and Disease. The Neuroscientist 1-15.

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Kurkowska Z, Brundin P, Schwab ME, Li JY (2014). Intracellular Nogo-A facilities initiation of neurite formation in mouse midbrain neurons in vitro. Neuroscience 256:456-466

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Bachmann LC, Lindau NT, Felder P, Schwab ME (2014). Sprouting of Brainstem-Spinal Tracts in Response to Unilateral Motor Cortex in Mice. The Journal of Neuroscience 34(9):3378-3389

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Manns R, Schmandke A, Schmandke A, Jareonsettasin P, Cook G, Schwab ME, Holt C, Keynes R (2014). Protein Synthesis Dependence of Growth Cone Collapse Induced by Different Noto-A Domains. PLOS One 9:1:e86820

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Wahl AS, Schwab ME (2014). Finding an optimal rehabilitation paradigm after stroke: enhancing fiber growth and training of the brain at the right moment. Frontiers: 7:9, 1-13

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Kempf A, Tews B, Arzt ME, Weinmann O, Obermair FJ, Pernet V, Zagrebelsky M, delekate A, Iobbi C, Zemmar A, Ristic Z, Gullo M, Spies P, Dodd D, Gygax D, Korte M, Schwab ME (2014). The Sphingolipid receptor S1PR2 is a Receptor for Nogo-A Repressing Synaptic Plasticity. PLOS Biology (12)1:e1001763

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Petrasek T, Prokopopova I, Bahnik S, Schonig K, Berger S, Vales K, Tews B, Schwab ME, Bartsch D, Stuchlik A (2014).Nogo-A downregulation impairs place avoidance in the Carousel maze but not spatial memory in the Morris water maze. Neurobiology of Learning and Memory 107: 42-49.

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Schmandke A, Mosberger AC, Schmandke A, Celen Zeliha, Schwab ME (2014). The neurite growth inhibitory protein Nogo-A has diverse roles in adhesion and migration. Cell Adhsion & Migration 07:461-464

2013

Willi R., Schwab ME. (2013). Nogo and Nogo receptor: relevance to schizophrenia?. Neurobiol Dis. 54: 150-7.

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Schmandke A, Schmandke A, Pietro M A, Schwab ME (2013). An open source based high content screening method for Cell Biology laboratories investigation cell spreading and adhesion. PLos ONE 8(10).

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Pernet V, Joly S, Dalkara D, Jordi N, Schwarz O, Christ F, Schaffer DV, Flannery JG, Schwab ME (2013). Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve. Elsevier 51:202-13.

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Kempf A, Montani L, Petrinovic MM, Schroeter A, Weinmann O, Patrignani A, Schwab ME (2013). Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration. Eur J Neurosci. doi:10.1111/ejn.12357.

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Hoogewoud F, Hamadjida A, Wyss AF, Mir A, Schwab ME, Belhaj-Saif A, Rouiller EM (2013). Comparison of functional recovery of manual dexterity after unilateral spinal cord lesion or motor cortex lesion in adult macaque monkeys. Front Neurol. 4:101.

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Pernet V, Joly S, Jordi N, Dalkara D, Guzik-Kornacka A, Flannery JG, Schwab ME (2013). Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve.

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Zhao RR, Andrews MR, Wang D, Warren P, Gullo M, Schnell L, Schwab ME, Fawcett JW (2013). Combination treatment with anti-Nogo-A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury. Eur J Neurosci.

Kempf A, Schwab ME (2013). Nogo-A represses anatomical and synaptic plasticity in the central nervous system. Physiology (Bethesda). 28(3):151-63.

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Wälchli T, Pernet V, Weinmann O, Shiu JY, Guzik-Kornacka A, Decrey G, Yüksel D, Schneider H, Vogel J, Ingber DE, Vogel V, Frei K, Schwab ME (2013). Nogo-A is a negative regulator of CNS angiogenesis. PNAS 110(21):E1943-52.

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Tews B, Schönig K, Arzt ME, Clementi S, Rioult-Pedotti MS, Zemmar A, Berger SM, Schneider M, Enkel T, Weinmann O, Kasper H, Schwab ME, Bartsch D (2013). Synthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive function. PNAS 110(16):6583-8.

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Bonal CB, Baronnier DE, Pot C, Benkhoucha M, Schwab ME, Lalive PH, Herrera PL (2013). Nogo-A downregulation improves insulin secretion in mice.Diabetes 62(5):1443-52.

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Petrinovic MM, Hourez R, Aloy EM, Dewarrat G, Gall D, Weinmann O, Gaudias J, Bachmann LC, Schiffmann SN, Vogt KE, Schwab ME (2013). Neuronal Nogo-A negatively regulates dendritic morphology and synaptic transmission in the cerebellum. PNAS 110(3)1083-1088.

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2012

Starkey L, Bleul C, Zörner B, Lindau NT, Mueggler T, Rudin M, and Schwab ME (2012). Back seat driving: hindlimb corticospinal neurons assume forelimb control following ischemic stroke. Brain, 135(Pt 11):3265-81.

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Willi R, Winter C, Wieske F, Kempf A, Yee B, Schwab ME, and Singer P (2012). Loss of EphA4 impairs short-term spatial recognition memory performance and locomotor habituation. Genes Brain and Behav. 11: 1020-1031.

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Rolando C, Parolisi R, Boda E, Schwab ME, Rossi F and Buffo A (2012). Distinct roles of Nogo-A and Nogo receptor 1 in the homeostatic regulation of adult Neural Stem Cell function and neuroblast migration. J. Neurosci., 32:17788-17799.

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Hamadjida A, Wyss AF, Mir A, Schwab ME, Belhaj-Saif A, Rouiller EM (2012). Influence of anti-Nogo-A antibody treatment on the reorganization of collosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult macaque monkeys. Ex Brain Res 223:321-340.

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Beaud ML, Rouiller EM, Bloch J, Mir A, Schwab ME, Wannier T, and Schmidlin E (2012). Invasion of lesion territory by regenerating fibers after spinal cord injury in adult macaque monkeys. Neuroscience 277: 271-282.

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Kapitza S, Zörner B, Weinmann O, Bolliger M, Filli L, Dietz V, Schwab ME (2012). Tail spasms in rat spinal cord injury: Changes in interneuronal connectivity. Exp. Neurol. 236:179-189.

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Ghosh A, Peduzzi S, Snyder M, Schneider R, Starkey M, and Schwab ME (2012). Heterogeneous Spine Loss in Layer 5 Cortical Neurons after Spinal Cord Injury. Cereb Cortex 22: 1309-1317.

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Pernet V, Schwab ME (2012). The role of Nogo-A in axonal plasticity, regrowth and repair. Cell Tissue Res 349: 97-104.

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Schwab ME, Buchli A (2012). Plug the real brain drain. Nature 483:267-268.

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2011

Pernet V, Joly S, Dalkara D, Schwarz O, Christ F, Schaffer D, Flannery JG, Schwab ME (2011). Neuronal Nogo-A upregulation does not contribute to ER stress-associated apoptosis but participates in the regenerative response in the axotomized adult retina. Cell Death Differ. 2011 Dec 23. doi: 10.1038/cdd.2011.191. [Epub ahead of print] PMID:22193546 [PubMed - as supplied by publisher]

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Schnell L, Hunanyan AS, Bowers WJ, Horner PJ, Federoff HJ, Gullo M, Schwab ME, Mendell LM, Arvanian VL. (2011). Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. Eur J Neurosci. 2011 Oct;34(8):1256-67. doi: 10.1111/j.1460-9568.2011.07862.x. Epub 2011 Oct 13.

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Starkey ML, Bleul C, Maier IC, and Schwab ME (2011). Rehabilitative training following unilateral pyramidotomy in adult rats improves forelimb function in a non-task-specific way. Experimental Neurology 232(1): 81-89.

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Gonzenbach RR, Zoerner B, Schnell L, Weinmann O, Mir A, and Schwab ME (2011). Delayed anti-Nogo-A antibody application after spinal cord injury shows progressive loss of responsiveness. J Neurotrauma. (E-pub ahead of print.)

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Ghosh A, Peduzzi S, Snyder M, Schneider R, Starkey M, and Schwab ME (2011). Heterogeneous Spine Loss in Layer 5 Cortical Neurons after Spinal Cord Injury. Cereb Cortex. (E-pub ahead of print.)

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Filli L, Zorner B, Weinmann O, and Schwab ME (2011). Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome. Brain 134: 2261-2273.

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Starkey ML, Schwab ME (2011). Anti-Nogo-A and training: Can one plus one equal three? Exp. Neurol. (E-pub ahead of print.)

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Delekate A, Zagrebelsky M, Kramer S, Schwab ME, and Korte M (2011). Nogo A restricts synaptic plasticity in the adult hippocampus on a fast time scale. Proc Natl Acad Sci USA 108: 2569-2574.

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Tsai SY, Papadopoulos CM, Schwab ME, Kartje GL (2011). Delayed anti-nogo-a therapy improves function after chronic stroke in adult rats. Stroke 42:186-90.

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2010

Schwab ME (2010) How hard is the CNS hardware? Nat Neurosci 13:1444-6.

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Schwab ME. (2010) Functions of Nogo proteins and their receptors in the vervous system. Nat Rev Nerusoci. 11(12): 799-811, Epub 2010 Nov 3.

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Zagrebelsky M, Schweigreiter R, Bandtlow CE, Schwab ME, Korte M. (2010) Nogo-A stabilizes the architecture of hippocampal neurons. J Neurosci. 30(40):13220-34.

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Zörner B, Filli L, Starkey ML, Gonzenbach R, Kasper H, Röthlisberger M, Bolliger M, Schwab ME (2010) Profiling locomotor recovery: comprehensive quantification of impairments after CNS damage in rodents. Nat Methods 7: 701-8.

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Gillani RL, Tsai S-Y, Wallace DG, O’Brien TE, Arhebamen E, Tole M, Schwab ME, Kartje GL. (2010) Cognitive recovery in the aged rat after stroke and anti-Nogo-A immunotherapy. Behavioural Brain Research 208: 415-424.

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Petrinovic MM, Duncan CS, Bourikas D, Weinman O, Montani L, Schroeter A, Maerki D, Sommer L, Stoeckli ET, Schwab ME (2010) Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development 137: 2539-2550.

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Gonzenbach RR, Gasser P, Zörner B, Hochreutner E, Dietz V, Schwab ME (2010) Nogo-A antibodies and training reduce muscle spasms in spinal cord-injured rats. Ann Neurol 68:48-57.

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Mathis C, Schröter A, Thallmair M and Schwab ME (2010) Nogo-A regulates neural precursor migration in the embryonic mouse cortex. Cerebral Cortex 20:2380-2390

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Kilic E, Elali A, Kilic U, Guo Z, Ugur M, Uslu U, Bassetti CL, Schwab ME, Hermann DM (2010) Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab 30:969-984.

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Joset A, Dodd DA, Halegoua S and Schwab ME (2010) Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling. J Cell Biol 188:271-285.

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Willi R, Weinmann O, Winter C, Klein J, Sohr R, Schnell L, Yee BK, Feldon J, Schwab ME (2010) Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes. J Neurosci 30:556-567.

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Ghosh A, Haiss F, Sydekum E, Schneider R, Gullo M, Wyss MT, Mueggler T, Baltes C, Rudin M, Weber B, Schwab ME (2010) Rewiring of hindlimb corticospinal neurons after spinal cord injury. Nat Neurosci 13:97-104.

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2009

Ghosh A, Sydekum E, Haiss F, Peduzzi S, Zorner B, Schneider R, Baltes C, Rudin M, Weber B, Schwab ME (2009) Functional and anatomical reorganization of the sensory-motor cortex after incomplete spinal cord injury in adult rats. J Neurosci 29:12210-12219. PDF (PDF, 2365 KB)

Maier IC, Ichiyama RM, Courtine G, Schnell L, Lavrov I, Edgerton VR, Schwab ME (2009) Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury. Brain. 2009 132:1426-40. PDF (PDF, 881 KB)

Montani L, Gerrits B, Gehrig P, Dimou L, Wollscheid B, Schwab ME (2009) Neuronal Nogo-A modulates growth cone motility via RhoGTP/LIMK1/cofilin in the unlesioned adult nervous system. J Biol Chem 284: 10793-807. PDF (PDF, 1185 KB)

Arvanian VL, Schnell L, Lou L, Golshani R, Hunanyan A, Ghosh A, Pearse DD, Robinson JK, Schwab ME, Fawcett JF, Mendell LM (2009) Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Exp Neurol 216:471–480. PDF (PDF, 779 KB)

Caelers A, Monge A, Michael J, Schwab ME, Bodmer D (2009) Nogo in the Mammalian cochlea. Otol Neurotol 30:668-675 PDF (PDF, 1243 KB)

Freund P, Schmidlin E, Wannier T, Bloch J, Mir A, Schwab ME, Rouiller EM (2009) Anti-Nogo-A antibody treatment promotes recovery of manual dexterity after unilateral cervical lesion in adult primates – re-examincation and extension of behavioral data. Eur J Neurosci 29:983–996 PDF (PDF, 1121 KB)

Willi R, Aloy EM, Yee BK, Feldon J, Schwab ME (2009) Behavioral characterization of mice lacking the neurite growth inhibitor Nogo-A. Genes Brain Behav 8:181–192. PDF (PDF, 552 KB)

Sydekum E, Baltes C, Ghosh A, Mueggler T, Schwab ME, Rudin M (2009) Functional reorganization in rat somatosensory cortex assessed by fMRI: Elastic image registration based on structural landmarks in fMRI images and application to spinal cord injured rats. Neuroimage 44: 1345-1354. PDF (PDF, 657 KB)

2008

Craveiro LM, Hakkoum D, Weinmann O, Montani L, Stoppini L, Schwab ME (2008) Neutralization of the membrane protein Nogo-A enhances growth and reactive sprouting in established organotypic hippocampal slice cultures. Eur J Neurosci 28: 1808-1824. PDF (PDF, 1082 KB)

Maier IC, Baumann K, Thallmair M, Weinmann O, Scholl J, Schwab ME (2008) Constraint-induced movement therapy in the adult rat after unilateral corticospinal tract injury. J Neurosci 28:9386-9403. PDF (PDF, 852 KB)

Cheatwood JL, Emerick AJ, Schwab ME, Kartje GL (2008) Nogo-A Expression After Focal Ischemic Stroke in the Adult Rat. Stroke 39:2091-2098. PDF (PDF, 639 KB)

Pernet V, Joly S, Christ F, Schwab ME (2008) Nogo-A and MAG differently regulate oligodendrocyte maturation and myelin formation. J Neurosci 28:7435-44. PDF (PDF, 11508 KB)

Wannier-Morino P, Schmidlin E, Freund P, Belhaj-Saif A, Bloch J, Mir A, Schwab ME, Roullier EM, Wannier T (2008) Fate of rubrospinal neurons after unilateral section of the cervical spinal cord in adult macaque monkeys: Effects of an antibody treatment neutralizing Nogo-A. Brain Res 1217:96-109. PDF (PDF, 1829 KB)

Endres M, Engelhardt B, Koistinaho J, Lindvall O, Mohr JP, Planas A, Schwaninger M, Schwab ME, Vivien D, Dirnagl U (2008) Improving outcome after stroke: overcoming the translational roadblock. Cerebrovasc Dis 25:268-278.

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Bourquin C, van der Haar ME, Anz D, Sandholzer N, Neumaier I, Endres S, Skerra A, Schwab ME, Linington, C (2008) DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune. Eur J Pharmacol 588:99-105. PDF (PDF, 1353 KB)

Brenneman MM, Wagner SJ, Cheatwood JL, Heldt SA, Corin JV, Reep RL, Kartje GL, Mir AK, Schwab ME (2008) Nogo-A inhibition induces recovery from neglect in rats. Behav Brain Res 5:262-72. PDF (PDF, 819 KB)

Dupuis L, Pehar M, Cassina P, Rene F, Castellanos R, Rouaux C, Gandelman M, Dimou L, Schwab ME (2008) Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proc Natl Acad Sci USA 15:740-5. PDF (PDF, 1123 KB)

Beaud ML, Schmidlin E, Wannier T, Freund P, Bloch J, Mir A, Schwab ME, Rouillier EM (2008) Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. BMC Neurosci 14:5. PDF (PDF, 440 KB)

Brenneman MM, Wagner SJ, Cheatwood JL, Heldt SA, Corwin JV, Reep RL, Kartje GL, Mir AK, Schwab ME (2008) Nogo-A inhibition induces recovery from neglect in rats. Behav Brain Res 187:262-72. PDF (PDF, 819 KB)

Muellner A, Gonzenbach R, Weinmann O, Schnell L, Liebscher T, Schwab ME (2008) Lamina specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury. Eur J Neurosci 27:326-333. PDF (PDF, 627 KB)