The Pfizer Research Award Foundation has handed out its prestigious awards, worth a total of 165,000 Swiss francs, to scientists for the 27th year running. Eighteen researchers were chosen for their excellent scientific work at Swiss research institutions or hospitals. Seven of the award winners work at the University of Zurich or the University’s hospitals. You can read about their research projects below.
How vessels develop in the brain
Despite considerable research, it’s still not known today which cellular and molecular mechanisms influence the development of vessels in the central nervous system. As a consequence, growth of these vessels cannot yet be affected therapeutically. The research of Thomas Wälchli from the Institute of Regenerative Medicine and his colleagues aimed to describe the effect of the nogo-A inhibitor on the development of blood vessels. The team of researchers was able to demonstrate that nogo-A inhibitors have an inhibiting effect on the growth of capillary vessels and the development of capillary vessel networks. These findings are important for future research into diseases such as brain tumors, vascular malformations, and strokes.